Alternatives to PayPal That Accept American Express

National Merchant Bancard
National Merchant Bancard offers services similar to PayPal and accepts all major credit cards, including American Express. The company caters to proprietors of online stores and services with registered accounts. You can set up a virtual credit-card terminal that processes payments in real time and accept instant payments that are deposited directly into your account. As of 2010, application and setup are free, and a $7.95 monthly account fee applies. There is also an option to receive a free credit-card processing terminal with printer you can use on-site.
MultiCards
MultiCards offers online credit-card and debit-card processing services to online retailers worldwide. It accepts payments from Visa, MasteCard, Discover, American Express and more. There are no monthly fees and no statement fees, it offers free online support and, according to the website, 'Almost any business accepted.' Some notable features include credit-card or debit-card processing in real time with instant verification, credit-card fraud detection services and acceptance of payments in USD, EURO or GBP. MultiCards Internet payment services can be integrated with most web-store shopping cart solutions.
2Checkout
2Checkout is an Internet payment service that offers many of the same features as PayPal and accepts all major credit cards, including American Express. You can create a business profile, enter product information and photos, create product buttons, apply 2Checkout to existing shopping carts on your websites and even accept PayPal payments. Before your account can be activated, your website and products must be reviewed to ensure they meet the terms and conditions of the company. As of 2010, 2Checkout registration requires a one-time-only charge of $49. Once you're up and running, you'll be charged a 5.5 percent commission on each sale and charged 45 cents per sale.